This shop is for commercial customers only.
  • XELL Europe
  • XELL USA
CHOlean | Medium

CHOlean | Medium

If you are from the EU or Switzerland, please sign in or register as a commercial customer in order to view prices and purchase our products. Customers from other countries, please contact us directly to get a quote.
  • 1140-0001
- Your lean and robust growth medium for various applications with unmatched pricing... more
Product information "CHOlean | Medium"

- Your lean and robust growth medium for various applications with unmatched pricing opportunities -

CHOlean Medium is a complete chemically defined, animal-component-free, protein-free, and ready-to-use cell culture medium. It has a lean medium formulation designed for batch and fed-batch processes with different CHO cell lines. CHOlean is developed with a minimal set of well-balanced components to achieve a lean, robust and flexible medium basis. In addition, it is capable of competing with state-of-the-art media for highest cell growth and product titer. CHOlean is optimized for easy adaptation from other media and is a robust platform to build high-performance fed-batch processes on. The medium supports cell growth and production of recombinant proteins and antibodies in suspension culture. It can be used in research or in manufacturing applications.

  • Suitable for various CHO clones (e.g., DG44, K1, CHO S, CHO GS)
  • Chemically defined, serum-free, animal component-free and hydrolysate-free
  • Little or no adaptation required from other serum-free media
  • Supports stable growth of suspension cells at high viability in seed train culture
  • w/o L-glutamine
  • w/o growth factor
  • w/o HT (hypoxanthine/thymidine)
  • Approved by ISO 9001 QMS (Quality Statement)

Customization of this product is available e.g., as SILAC/ deficiency variant. Contact us for more information.

 CHOlean-Performance

Figure 1: Relative titers (bars) and maximum viable cell densities (VCD, rhombs) of two CHO cell lines in CHOlean compared to current state-of-the-art, chemically defined, ADCF expression media for CHO suspension cells of five different competitors.

 

CHOlean-Number-of-Components

Figure 2: Number of components of different classes (amino acids, vitamins, salts, buffer, iron and others) of CHOlean compared to the basal formulation DMEM/Ham's F12 as well as the comparison of total number of components of CHOlean, DMEM/Ham's F12 and some state-of-the-art production media.

Related links to "CHOlean | Medium"
Available downloads:
Additional Information "CHOlean | Medium"
TCX6D | Medium TCX6D | Medium
- Well performing medium for any CHO clone - flexible medium for stable production in batch or fed-batch processes - TCX6D...
TC-42 w/ IGF | Medium TC-42 w/ IGF | Medium
- Optimal medium for various CHO processes - free of HT - TC-42 w/IGF is a complete chemically defined ,...
TC-42 w/o GF | Medium TC-42 w/o GF | Medium
- Optimal medium for various CHO processes - free of HT - TC-42 w/o GF is a complete chemically defined ,...
TC-42 w/ rInsulin | Medium TC-42 w/ rInsulin | Medium
- Optimal medium for various CHO processes - free of HT - TC-42 w/rInsulin is a complete chemically defined ,...
TCX10D | Medium TCX10D | Medium
- The right choice for high-performance and long-term production with CHO GS cells - TCX10D Medium is a complete chemically...
CHO TF | Medium CHO TF | Medium
- Perfect medium for working with transient CHO cells - growth, transfection and production - CHO TF is a complete chemically...
Basic Feed | Feed Basic Feed | Feed
- Single feeding solution optimzied for various cells and processes -  Basic Feed is a chemically defined , animal...
TCX6D | Medium TCX6D | Medium
- Well performing medium for any CHO clone - flexible medium for stable production in batch or fed-batch processes - TCX6D...
TC-42 w/ IGF | Medium TC-42 w/ IGF | Medium
- Optimal medium for various CHO processes - free of HT - TC-42 w/IGF is a complete chemically defined ,...
TCX10D | Medium TCX10D | Medium
- The right choice for high-performance and long-term production with CHO GS cells - TCX10D Medium is a complete chemically...
TC-42 w/o GF | Medium TC-42 w/o GF | Medium
- Optimal medium for various CHO processes - free of HT - TC-42 w/o GF is a complete chemically defined ,...
TCX7D | Feed TCX7D | Feed
- The best option for fed-batch processes and in combination with TCX10D - for optimal nutrition of CHO GS cells - The TCX7D...
Hint!
HEK ViP NX | Medium HEK ViP NX | Medium
- Optimized virus production - best choice for transient expression in HEK cells - HEK ViP NX is a complete chemically defined...
Hint!
HEK FS | Feed HEK FS | Feed
- Unique on the marked - Ideal boost for production of viral vectors, vaccines, proteins - HEK FS is a chemically defined ,...
HEK GM | Medium HEK GM | Medium
- Your best choice for stable expression with HEK cells - robust and effective - HEK GM is a complete chemically defined ,...
TC-42 w/ rInsulin | Medium TC-42 w/ rInsulin | Medium
- Optimal medium for various CHO processes - free of HT - TC-42 w/rInsulin is a complete chemically defined ,...
HEK TF | Medium HEK TF | Medium
- Well established transfection medium - ideal for production of recombinant proteins and antibodies - HEK TF is a complete...
HEK ViP NB | Medium HEK ViP NB | Medium
- Optimized virus production - best choice for transient expression in HEK cells - HEK ViP NB is a complete chemically defined...
CAP®-CDM | Medium CAP®-CDM | Medium
- Best fit - High performance medium for Cevec's CAP®-Go cell lines - CAP ® -CDM is a complete chemically defined ,...
MDXK Medium MDXK Medium
-Well performing and robust medium for high-density cultivation and production with MDCK and MDBK cells - MDXK Medium is a...
AXP - dry powder manufacture AXP - dry powder manufacture
Accelerated Xell Production (AXP) - manufacture of customized dry powder formulations (Animal Origin Free only).  After...
BHK Medium BHK Medium
- Your best fit for stable production with BHK cells - ideal for vaccine production and suitable for microcarriers - BHK Medium...
Customized Medium and Feed Development Customized Medium and Feed Development
Xell offers targeted, rapid and efficient services for the development of custom cell culture medium and feed and is your ideal...
HYB GM | Medium HYB GM | Medium
- Lean and high-performance Hybridoma medium - easy scale-up - HYB GM is chemically defined and serum-free cell culture...
Medium and Feed Screenings/Benchmarkings Medium and Feed Screenings/Benchmarkings
Cell culture medium and feed selection typically involves screening and benchmarking of alternative off-the-shelf culture media...
Cell Line Adaptation Cell Line Adaptation
We adapt your adherently growing cell line to (suspension) growth in a suitable serum-free, chemically defined cell culture medium...
Amino acid Analysis Amino acid Analysis
With our amino acid measurement (order no. 103) free amino acids are measured, whereas with our total amino acid analysis (order...
BHK FS | Feed BHK FS | Feed
- Perfect boost for vaccine production with BHK cells - The BHK FS is a chemically defined , animal component-free cell...
Screening Kit – Serum Free Media Screening Kit – Serum Free Media
  Our screening kit is the easiest approach for you to test, identify and select the best matching serum-free and...
Cell Studies (stability, characterization) Cell Studies (stability, characterization)
With our broad range of analytical methods (cell growth, product quantification and qualification, flow cytometry applications), we...
Lot-to-lot testing Lot-to-lot testing
Lot-to-lot variation is a well-known effect in media production and can occur even in chemically defined media. It can be caused...
Raw Material or Supplier Evaluation Raw Material or Supplier Evaluation
With our key competences in medium development and manufacture, we know that raw materials (production, origin, quality) and...
CAP®-CDM Feed CAP®-CDM Feed
- Best fit in combination with CAP Medium - High performance feed for Cevec's CAP®-Go cell lines - CAP ® -CDM Feed is a...
Consulting Consulting
Whether you are just starting to set up a cell culture lab, experiencing process limitations, seeing batch-to-batch variations of...
HYB FS | Feed HYB FS | Feed
- Best choice for fed-batch processes and in combination with HYB GM or Hybrioma Base Medium - for ideal nutrition of Hybridoma...
Hint!
Hybridoma Base Medium Hybridoma Base Medium
- Optimized for the demanding metabolism of Hybridoma cells and mAbs production - Hybridoma Base Medium is chemically defined...
Dry powder rehydration service Dry powder rehydration service
Rehydration of dry powder formulations (Animal Origin Free only). Rehydration within 10 business days after receipt of dry...
Process Development and Optimization Process Development and Optimization
Process development such as feed strategy optimization can take up a lot of time and resources. With our long-standing experience...
Culture Media Analysis Bundle Culture Media Analysis Bundle
Spent media analysis is the analysis of the used media over the course of the production process and facilitates the selection of...
Trace Element Analysis Bundle for Spent Media Trace Element Analysis Bundle for Spent Media
Trace elements are determined by ICP-MS, combining highest sensitivity with excellent reliability, including: Element...
HEK TF | Medium Sample HEK TF | Medium Sample
HEK TF is a complete chemically defined , animal-component-free medium. It was developed by Xell for cultivation of HEK and other...
Vero GM | Medium Vero GM | Medium
- The right choice for high-performance and long-term production with Vero cells - Vero GM is a complete chemically defined ,...
Basic Feed Sample Basic Feed Sample
The Basic Feed is a chemically defined , animal component-free cell culture medium supplement . It is developed for the use as...
Coulometric Karl-Fischer Titration Coulometric Karl-Fischer Titration
Determination of water content in solid and liquid samples using coulometric Karl-Fischer titration. Quantification range: 1 ppm...
Analysis of Total Amino Acid Content Analysis of Total Amino Acid Content
With our amino acid measurement (order no. 103) free amino acids are measured, whereas with our total amino acid analysis (order...