This shop is for commercial customers only.
Lot-to-lot testing

Lot-to-lot testing

Please contact us to get more details about this product.
  • 43
Lot-to-lot variation is a well-known effect in media production and can occur even in chemically... more
Product information "Lot-to-lot testing"

Lot-to-lot variation is a well-known effect in media production and can occur even in chemically defined media. It can be caused e.g. by change of raw materials, minor changes in the powder production process or the solubilization procedure. Furthermore, lot-to-lot variation can occur due to impurities in raw materials. Components such as amino acids in USP/pharma grade with ≥ 98-99% purity may still contain foreign amino acids and trace metals. To evaluate variation in your media lots, we highly recommend biological performance tests and respective analytics. For that, we can establish and perform routine lot testing.

Please contact us to discuss your individual study requirements.

Related links to "Lot-to-lot testing"
Medium and Feed Screenings/Benchmarkings Medium and Feed Screenings/Benchmarkings
Cell culture medium and feed selection typically involves screening and benchmarking of alternative off-the-shelf culture media...
Consulting Consulting
Whether you are just starting to set up a cell culture lab, experiencing process limitations, seeing batch-to-batch variations of...
Cell Studies (stability, characterization) Cell Studies (stability, characterization)
With our broad range of analytical methods (cell growth, product quantification and qualification, flow cytometry applications), we...
Process Development and Optimization Process Development and Optimization
Process development such as feed strategy optimization can take up a lot of time and resources. With our long-standing experience...
Customized Medium and Feed Development Customized Medium and Feed Development
Xell offers targeted, rapid and efficient services for the development of custom cell culture medium and feed and is your ideal...
Cell Line Adaptation Cell Line Adaptation
We adapt your adherently growing cell line to (suspension) growth in a suitable serum-free, chemically defined cell culture medium...
CAP®-CDM CAP®-CDM
CAP ® -CDM is a chemically defined growth and production medium designed by Xell for Cevec's CAP ® -Go cell lines. Chemically...
TCX6D TCX6D
Growth and expression medium for various CHO cell lines. Chemically defined, serum-free, animal component-free and...
Basic Feed Basic Feed
Basic Feed is a feed supplement for prolonged production of biologics in fed-batch processes, suitable for a broad range of cell...
TCX7D TCX7D
Advanced feed supplement for CHO fedbatch processes. Chemically defined, serum-free, animal component-free and hydrolysate-free...
Raw Material or Supplier Evaluation Raw Material or Supplier Evaluation
With our key competences in medium development and manufacture, we know that raw materials (production, origin, quality) and...
CHOlean CHOlean
Growth and expression medium for various CHO cell lines. Chemically defined, serum-free, animal component-free and...
TC-42 w/ rInsulin TC-42 w/ rInsulin
Growth and expression medium for various CHO cell lines. Chemically defined, serum-free, animal component-free and...
TC-42 w/ IGF TC-42 w/ IGF
Growth and expression medium for various CHO cell lines. Chemically defined, serum-free, animal component-free and...
CHO TF CHO TF
Specifically designed to support efficient transfection and high-density suspension cultivation, CHO TF is particularly suited for...
TCX10D TCX10D
Growth and expression medium for CHO GS and other CHO cell lines. Chemically defined, serum-free, animal component-free and...
Dry powder rehydration service Dry powder rehydration service
Rehydration of dry powder formulations (Animal Origin Free only). Rehydration within 10 business days after receipt of dry...
AXP - liquid formulation production AXP - liquid formulation production
Manufacture of customized liquid formulations (Animal Origin Free only). Production is based on a non-disclosure agreement. After...
AXP - dry powder manufacture AXP - dry powder manufacture
Manufacture of customized dry powder formulations (Animal Origin Free only). Production is based on a non-disclosure agreement....
TC-42 w/o GF TC-42 w/o GF
Growth and expression medium for various CHO cell lines. Chemically defined, serum-free, animal component-free and...
Trace element analysis Trace element analysis
Trace elements are determined by ICP-MS, combining highest sensitivity with excellent reliability, including: Element...
BHK FS BHK FS
Advanced supplement for BHK fedbatch processes. Chemically defined, serum-free, animal component-free and hydrolysate-free...
HEK TF HEK TF
Specifically designed to support high-density suspension cultivation and efficient transfection, HEK TF is particularly suited for...
Endotoxin Analysis - FAF Endotoxin Analysis - FAF
The LAL (Limulus amoebocyte lysate) test is used to detect and/or quantify endotoxins from gram-negative bacterial origin. Endosafe...
Ammonium analysis - FAF Ammonium analysis - FAF
Assay for the determination of ammonium concentrations. The average LOQ is 0.1 mM and might vary depending on the matrix.
Trace element analysis - FAF Trace element analysis - FAF
Trace elements are determined by ICP-MS, combining highest sensitivity with excellent reliability, including: Element...
Ion analysis Ion analysis
Measurement of Sodium, Potassium, Phosphate, Calcium and Magnesium using ion-selective electrodes.
HYB GM HYB GM
HYB GM Medium is a lean high-performance medium for antibody production in various hybridomas. Chemically defined, serum-free,...
Culture media analysis bundle Culture media analysis bundle
The comprehensive culture media analysis bundle includes the analysis of glucose and lactate , amino acids , water-soluble...
Hybridoma Base Medium Hybridoma Base Medium
Hybridoma Base Medium is a lean high-performance medium for antibody production in various hybridomas. Chemically defined,...
MDXK Medium MDXK Medium
Growth and production medium for MDCK and MDBK cell lines. Chemically defined, serum-free, animal component-free and...
HEK FS HEK FS
Feed supplement to boost process yields of human cell cultures, e.g. HEK. Chemically defined, serum-free, animal component-free...
TCX10D Sample TCX10D Sample
Growth and expression medium for CHO GS and other CHO cell lines. Chemically defined, serum-free, animal component-free and...
TCX7D Sample TCX7D Sample
Advanced feed supplement for CHO fedbatch processes. Chemically defined, serum-free, animal component-free and hydrolysate-free...
Phosphate Analysis - FAF Phosphate Analysis - FAF
Photometric assay for the quantitative analysis of inorganic phosphate (ortho-phosphate).
Organic Acid Analysis - Colorimetric Assay -FAF Organic Acid Analysis - Colorimetric Assay -FAF
Organic acid content is determined using abcam colorimetric kits in combination with Thermo Fisher multimode plate reader...
Glutathione analysis - FAF Glutathione analysis - FAF
UHPLC-MS/MS based measurement of glutathione (oxidized and reduced state). Please contact us for more information.
Dipeptide analysis - FAF Dipeptide analysis - FAF
UHPLC-MS/MS based measurement of dipeptides. Please contact us for more information.
Coulometric Karl-Fischer Titration - FAF Coulometric Karl-Fischer Titration - FAF
Determination of water content in solid and liquid samples using coulometric Karl-Fischer titration. Quantification range: 1 ppm -...
Glucose and lactate analysis - FAF Glucose and lactate analysis - FAF
Enzymatic-amperometric measurement of glucose and lactate.