Raw Material or Supplier Evaluation
- Order number: 42
Within the last few decades cell culture media has evolved from complex serum or hydrolysate containing base formulations to chemically defined, animal component-free or animal origin-free, high performance cell culture solutions. In parallel, the biopharmaceutical industry has increased its expectation regarding lot-to-lot consistency and traceability. These requirements thrust analysis of contamination of cell culture media raw materials into focus. Collection of such data will not only aid in an understanding of current cell culture media characteristics, it will also provide required data to assess reasonably or maintain media performance.
With our key competences in medium development and manufacture, we know that not only raw materials (production, origin, quality), but also production technology are crucial factors influencing the quality of the final medium product. As a result, the same medium formulation can lead to deviating process performances. We therefore offer to test raw material sources and to compare different suppliers. Furthermore, we recommend respective biological testing of potential raw materials and evaluation of products from different suppliers with regard to process performance and production. Powder and liquid media characterization as well as solubility studies of your products are also part of our portfolio.
Please contact us to discuss your individual study requirements.
Feel free to read and download our case study on Raw material control: Trace element contaminations of amino acids. Since amino acids are a major component of cell culture media, which also make up a significant percentage of the media- and feed- composition, we show how raw materials for amino acids from different suppliers can have different trace element impurities.