Xell offers a range of chemically-defined, high-performance, off-the-shelf culture media and feeds for various mammalian cell lines and applications.
All our state-of-the-art cell culture media and feed products are distinguished as follows:
In case you cannot find a suitable medium or feed for your application or cell, reach out, we are always open for developing customized solutions.
CHO cell lines are the most prevalent mammalian expression system in the biopharmaceutical industry. Frequently produced biotherapeutics range from monoclonal antibodies (mAbs) and recombinant proteins, to hormones, enzymes and many more. CHO cells can be used for both stable expression and transient expression. Based on diverse host and production clones, Xell has developed a CHO cell culture medium and feed platform that supports highly efficient protein expression and the individual characteristics of the various clones.
Xell’s CHO media and feeds are developed for long-term, high-performance suspension cultures. The media and feeds are suitable for research, as well as routine large-scale GMP manufacturing.
Human embryonic kidney (HEK) cells and other human cell lines are commonly used for stable expression and transient expression of recombinant proteins for research and therapeutic use. The well-established mammalian expression system, HEK293, is also widely used for the production of Adeno-associated viruses (AAV) and lentiviruses, viral vector production, as well as for gene therapy applications.
Xell’s HEK cell culture media and feeds are developed for long-term, high-performance suspension culture. The media and feeds are suitable for research, as well as routine large-scale GMP manufacturing.
Hybridomas are hybrid cell lines formed by fusion of a B cell (e.g., of mouse-origin) with an immortal B myeloma cell. Each hybridoma is able to constitutively produce one specific target monoclonal antibody (mAb). The mAbs that are produced are chemically identical, which qualifies them for various in vivo applications, such as diagnostics, therapeutics, targeted biologics, etc.
Xell’s Hybridoma cell culture media and feeds are optimized for the demanding metabolism of hybridoma cells, such as human, mouse and rat hybridomas and myelomas. The media and feeds are suitable for research, as well as the routine large-scale GMP manufacturing of mAbs.
Baby Hamster Kidney (BHK) cells are one of the most commonly used mammalian expression system for the production of biopharmaceuticals, recombinant proteins (e.g., Factor VIII) and vaccines (e.g., against SBV). BHK cells can be used for both, transient and stable expression.
Vero cells (African green monkey kidney) and Madin-Darby Canine/Bovine Kidney (MDCK/MDBK) cells are mammalian cell lines widely used in biological and biomedical research as well as in virus and vaccine production.
Xell offers cell culture media and feeds for BHK, Vero and MCBK/MDCK cells, optimized for the specific needs of each cell line. The cell culture media and feed solutions are suitable for research and routine large-scale GMP manufacturing.