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The key to an easier scale-up: Suspension-adapted cells

Traditional mammalian cell culture is usually anchor-dependent and serum-supplemented, which is directly connected to a series of disadvantages, due to the serum/ animal derived components. In contrast, suspension cultures in animal-derived component free (ADCF) cell culture media have several advantages:

  • reduced lot-to-lot variability of the medium
  • easier scale-up
  • no risk of blood-borne pathogens
  • massively reduced production costs
  • increased animal-welfare

Figure 1: General steps in the cell line adaptation process

Infographic depicting general steps in the cell line adaptation process.

Xell’s scientists have more than 20 years of experience with cell culture and state-of-the-art culture media. Adapting cell lines to serum-free suspension culture is just one of the many services we offer to the scientific community and biotechnology industry. Contact us to discuss your specific project.