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Biosafety level 2 Analytics

Biosafety level 2 Analytics

Please contact us to get more details about this product.
  • Analytics-S2
Do you have cell culture supernatants or spent medium that you would like to have analyzed, but... more
Product information "Biosafety level 2 Analytics"

Do you have cell culture supernatants or spent medium that you would like to have analyzed, but unfortunately your samples can only be handled in a Biosafety level 2 (BSL 2) lab, since they contain viruses or virus particles? Then we are the perfect partner for you.

For the measurement of amino acids, glucose and lactate we have already created the possibility to measure S2 samples. Trace elements can also be measured after autoclaving. 

Our proprietary, quantitative UHPLC-DAD method covers the following amino acids:

  • Alanine
  • Arginine
  • Asparagine
  • Aspartate
  • Citrulline
  • Cystine/Cysteine*
  • Glutamate
  • Glutamine
  • Glycine
  • Histidine
  • Hydroxyproline
  • Isoleucine
  • Leucine
  • Lysine
  • Methionine
  • Ornithine
  • Phenylalanine
  • Proline
  • Serine
  • Taurine
  • Threonine
  • Tryptophane
  • Tyrosine
  • Valine

 *Cysteine rapidly oxidizes to cystine. We will provide the absolute measured concentration of cystine, and a qualitative value for cysteine if detectable.

Glucose and Lactate are measured via an enzymatic-amperometric measurement.

Please contact our experts to find out more.

If you are interested in further analyzes for S2 samples, please get in touch! We will be happy to discuss your project.

Related links to "Biosafety level 2 Analytics"
Deliverables "Biosafety level 2 Analytics"

We will send you a short report summarizing your data within 10 business days*.

*After receipt of samples and if no additional sample preparation / matrix evaluation is necessary. Valid for sets of more than 5 samples.

Sample Requirements "Biosafety level 2 Analytics"

Usually a sample amount of 1 mg (if purity is > 80%) or 1 ml is needed for each analytical service. If you are limited in your sample amount please contact us. We are open to discuss smaller volumes. If you send frozen samples for more than one analysis, it would be desirable to ship them in aliquots, to prevent repeated freezing and thawing.

Due to potential matrix effects verification of sample feasibility might be necessary prior to analysis.

For Spent Media Samples:

 

For Food, Feed and other Samples:

  • Samples can be liquid or powder. Please contact us for individual support regarding sample preparation.
  • Please read and sign our sample declaration sheet.

 

For Metabolomic Samples:

  • Samples can be cell lysates or supernatants. Please contact us for individual support regarding sample preparation.
  • Please read and sign our sample declaration sheet.
Additional Information "Biosafety level 2 Analytics"
Amino acid Analysis Amino acid Analysis
With our amino acid measurement (order no. 103) free amino acids are measured, whereas with our total amino acid analysis (order...
Glucose and Lactate Analysis Glucose and Lactate Analysis
Enzymatic-amperometric measurement of glucose and lactate.
Trace Element Analysis Bundle for Spent Media Trace Element Analysis Bundle for Spent Media
Trace elements are determined by ICP-MS, combining highest sensitivity with excellent reliability, including: Element...
ELISA-based Analysis ELISA-based Analysis
As an immunological assay, the ELISA (enzyme-linked immunosorbent assay) can be applied for a broad range of cell culture derived...
qPCR-based Analysis qPCR-based Analysis
Analysis via qPCR (quantitative polymerase chain reaction) is extremely sensitive and can be utilized for detection of target...
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Trace Element Analysis Bundle for Spent Media Trace Element Analysis Bundle for Spent Media
Trace elements are determined by ICP-MS, combining highest sensitivity with excellent reliability, including: Element...
KONFIGURATOR
Element Analysis Bundle Element Analysis Bundle
Our ICP-MS method covers the following elemtents. Please select your elements of choice.
ELISA-based Analysis ELISA-based Analysis
As an immunological assay, the ELISA (enzyme-linked immunosorbent assay) can be applied for a broad range of cell culture derived...
Amino acid Analysis Amino acid Analysis
With our amino acid measurement (order no. 103) free amino acids are measured, whereas with our total amino acid analysis (order...
Customized Analytical Method Development Customized Analytical Method Development
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qPCR-based Analysis qPCR-based Analysis
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Bioburden Testing Bioburden Testing
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Polyamine Analysis Polyamine Analysis
Polyamine levels in mammalian cells play a key role in cells’ viability as well as protein synthesis. Knowing the polyamine content...
Water-soluble Vitamin Analysis Water-soluble Vitamin Analysis
Our UHPLC-MS/MS method covers the following water-soluble vitamins, vitaminoids and precursors*: Vitamin B1: Thiamine...
ADCC Reporter Bioassay ADCC Reporter Bioassay
Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism of cell-mediated immune response, initiated by specific...
Endotoxin Analysis Endotoxin Analysis
The LAL (Limulus amoebocyte lysate) test is used to detect and/or quantify endotoxins from gram-negative bacterial origin. Endosafe...
Glutathione Analysis Glutathione Analysis
UHPLC-MS/MS based measurement of glutathione (oxidized and reduced state). Please contact us for more information.
Analysis of Total Amino Acid Content Analysis of Total Amino Acid Content
With our amino acid measurement (order no. 103) free amino acids are measured, whereas with our total amino acid analysis (order...
Citrate Analysis Citrate Analysis
Citrate is measured via a photometric assay.
Ammonium Analysis Ammonium Analysis
Assay for the determination of ammonium concentrations. The average LOQ is 0.1 mM and might vary depending on the matrix.
Particle Size Distribution Particle Size Distribution
Determination of the particle size distribution in solid samples using Laser diffraction plus advanced Polarization Intensity...
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Organic Acid Analysis - UHPLC based method Organic Acid Analysis - UHPLC based method
Organic acid content is determined using UHPLC-MS. Citric acid, Fumaric acid, Lactic acid, Malic acid, Pyruvat, Succinic acid,...
Cell Studies (stability, characterization) Cell Studies (stability, characterization)
With our broad range of analytical methods (cell growth, product quantification and qualification, flow cytometry applications), we...
Process Development and Optimization Process Development and Optimization
Process development such as feed strategy optimization can take up a lot of time and resources. With our long-standing experience...
Dipeptide Analysis Dipeptide Analysis
UHPLC-MS/MS based measurement of dipeptides. Please contact us for more information.
Antibody Quantification Antibody Quantification
Our HPLC method for quantification of antibodies is based on protein A affinity chromatography. If you are unsure whether your...
Ascorbate Analysis Ascorbate Analysis
Quantitation of ascorbic acid (vitamin C) via a proprietary method by UHPLC-MS/MS.
Formulation Development Formulation Development
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Coulometric Karl-Fischer Titration Coulometric Karl-Fischer Titration
Determination of water content in solid and liquid samples using coulometric Karl-Fischer titration. Quantification range: 1 ppm...
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Lot-to-lot testing Lot-to-lot testing
Lot-to-lot variation is a well-known effect in media production and can occur even in chemically defined media. It can be caused...
Raw Material or Supplier Evaluation Raw Material or Supplier Evaluation
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AXP - dry powder manufacture AXP - dry powder manufacture
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Phosphate Analysis Phosphate Analysis
Photometric assay for the quantitative analysis of inorganic phosphate (ortho-phosphate).
Cell Line Adaptation Cell Line Adaptation
Traditional mammalian cell culture is usually anchor-dependent and serum-supplemented, which is directly connected to a series of...
Glucose and Lactate Analysis Glucose and Lactate Analysis
Enzymatic-amperometric measurement of glucose and lactate.
Pyridoxal Phosphate Pyridoxal Phosphate
Measurement of Pyridoxal Phosphate using UHPLC-MS/MS.
Highly abundant Cation Analysis Highly abundant Cation Analysis
Measurement of the highly abundant cations Sodium, Potassium, Magnesium, Calcium and Iron using ICP-MS.
Manufacturing Science Manufacturing Science
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Contract Manufacturing Service Contract Manufacturing Service
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Organic Acid Analysis - Colorimetric Assay Organic Acid Analysis - Colorimetric Assay
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AXP - liquid formulation production AXP - liquid formulation production
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